Showing posts with label DRUGS. Show all posts
Showing posts with label DRUGS. Show all posts

Tuesday 30 July 2013

Garlic an antifungal, garlic can also support your immune system, reduce cholesterol, and help control blood sugar levels.

garlic

Garlic is a proven antifungal . Research studies have shown that garlic is effective against pathogens like Candida. In addition to its use as an antifungal, garlic can support your immune system, reduce cholesterol, and help control blood sugar levels.
You can start taking garlic supplements once you have finished your cleanse and moved on to the strict anti-Candida diet. As always, it is better to take two or three antifungals at once to prevent the Candida from adapting, so you can use garlic in addition to other natural antifungals.

How does Garlic help with Candida overgrowth?

There is a wide range of scientific literature supporting the use of garlic as an antifungal. Much of this research is focused on Candida and similar pathogenic organisms. For example, a 1988 study (see the full text here) found that “the growth of Candida Albicans was found to be markedly inhibited by AGE [aqueous garlic extract]”. According to another article by Huntington College of Health Sciences, “Research has clearly shown that garlic has anticandidal activity, inhibiting both the growth and function of Candida Albicans”.
One of the key compounds in garlic is ajoene, a proven antifungal that has been shown to be effective against many fungal strains. Ajoene is formed from a compound named allicin and an enzyme named allinase. When these two natural compounds come into contact (by chopping the garlic, crushing it or by other means), they form an antibacterial agent named allicin, which then combines to form ajoene. Although this has proven antifungal properties, the exact mechanism by which this happens is not clear. As with other antifungals, scientists suspect that it works by disrupting the cells walls of the Candida yeast cells.
A major advantage of garlic is that it is so easy to include in your treatment plan. Garlic tablets, softgels and oils are widely available, and fresh garlic cloves make a tasty addition to many recipes. You can use garlic as a complement to your other antifungals without having to spend a great deal of money. To get the best results and prevent the Candida yeast from adapting to the treatment, it is best to take two or three antifungals at the same time.

How do you take Garlic?

Garlic products can be found in a number of different forms, in both your supermarket and your health food store. In your supermarket you will find items like fresh garlic cloves, garlic paste, crushed garlic, garlic flakes or garlic powder. Your health food store should stock garlic tablets and garlic oil.
Each type contains different levels of the active ingredients, so make sure to read the ingredients. Here is a basic run-down of the recommended dosage for each type:
  • Garlic cloves: 2 to 4 grams per day of fresh, minced garlic clove
  • Garlic Tablets: 600 to 900 mg daily, freeze-dried garlic standardized to 1.3% alliin or 0.6% allicin
  • Garlic Oil: 0.03 to 0.12 mL three times a day

Who should not take Garlic?

Although a natural remedy, concentrated garlic can still interact with other medicines, so always consult a health professional. Garlic has a blood-thinning property that can be very useful, but can also be dangerous to sufferers of hemophilia or platelet disorders, as well as pregnant women or patients about to undergo surgery.
Side effects from garlic include upset stomach, bloating, bad breath, body odor, and a stinging sensation on the skin from handling too much fresh or dried garlic. Handling garlic may also cause the appearance of skin lesions.
Other side effects that have been reported by those taking garlic supplements include headache, fatigue, loss of appetite, muscle aches, dizziness described as vertigo (namely, the room spinning), and allergies such as an asthmatic reaction or contact dermatitis (skin rash).
Some people may suffer a mild allergic reaction to concentrated garlic. Others may have an upset stomach, body odor, bad breath, headache, loss of appetite or fatigue. It may prompt a skin reaction, such as a stinging in the hands.

Monday 29 July 2013

Sanofi gets EU CHMP nod for a new formulation of Insuman for the treatment of type 1 diabetes


On 25 July 2013, the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the addition of a new formulation to the marketing authorisation of the medicinal product Insuman. The new formulation, Insuman Implantable, is an insulin solution for infusion (400 IU/ml) that is delivered into the intra-peritoneal cavity via an implantable pump device (MiniMed). It has been developed as a replacement for another insulin product called Insuplant, which is no longer manufactured
read at
http://www.pharmaintellect.com/2013/07/sanofi-gets-eu-chmp-nod-for-new.html?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+Pharmainvest+%28PharmaInvest%29
....

Thursday 25 July 2013

Scripps Research Institute Scientists Find a Potential Cause of Parkinson’s Disease that Points to a New Therapeutic Strategy







 For a high-resolution image see: http://www.scripps.edu/news/press/
images/reed_steve/reed_steve.jpg

LA JOLLA, CA – July 24, 2013 – Biologists at The Scripps Research Institute (TSRI) have made a significant discovery that could lead to a new therapeutic strategy for Parkinson’s disease.
The findings, recently published online ahead of print in the journal Molecular and Cell Biology, focus on an enzyme known as parkin, whose absence causes an early-onset form of Parkinson’s disease. Precisely how the loss of this enzyme leads to the deaths of neurons has been unclear. But the TSRI researchers showed that parkin’s loss sharply reduces the level of another protein that normally helps protect neurons from stress.
 http://www.scripps.edu/news/press/2013/20130724reed.html

Wednesday 24 July 2013

Isis Phase II drug APOIIIRx slashes triglycerides by 64%


Isis Pharmaceuticals is "very encouraged" by a second set of mid-stage data for its heart drugAPOIIIRx, which shows that it can substantially slash levels of dangerous fats in the blood. 

In a 26-patient Phase II trial, patients with severely high levels of triglycerides taking Isis' drug alongside fibrates experienced 64% drop in triglycerides, and a 70% drop in apolipoprotein C-III (apoC-III), a component of 'bad' low-density lipoprotein
read all at
.http://www.pharmatimes.com/Article/13-07-23/Isis_PhII_drug_slashes_triglycerides_by_64.aspx

Tuesday 23 July 2013

New therapy for pancreatic cancer: Phase III clinical trial currently recruiting Australian patients


Currently there is a clinical trial that is recruiting patients from around the globe including sites across Australia. The trial is testing MM-398; a therapy that uses the latest in nanotechnology to deliver the chemotherapeutic agent irinotecan encased in a liposome to cancer patients.1 In particular this trial, named NAPOLI-1 (NAnoliPOsomaL Irinotecan) is recruiting patients with pancreatic cancer who have previously been treated with the chemotherapy agent gemcitabine unsuccessfully i.e. their disease has gone on to spread/progress despite this treatment.2,3
read all here

http://www.virtualmedicalcentre.com/news/new-therapy-for-pancreatic-cancer-phase-iii-clinical-trial-currently-recruiting-australian-patients/18708


irinotecan

Irinotecan (Camptosar, Pfizer; Campto, Yakult Honsha) is a drug used for the treatment of cancer.
Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. In chemical terms, it is a semisynthetic analogue of the natural alkaloid camptothecin.
Its main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil,leucovorin, and irinotecan.
Irinotecan received accelerated approval by the U.S. Food and Drug Administration (FDA) in 1996 and full approval in 1998. During development, it was known as CPT-11.
Irinotecan is activated by hydrolysis to SN-38, an inhibitor of topoisomerase I. This is then inactivated by glucuronidation by uridine diphosphate glucoronosyltransferase 1A1 (UGT1A1). The inhibition of topoisomerase I by the active metabolite SN-38 eventually leads to inhibition of both DNA replication and transcription.


Merrimack currently has six oncology therapeutics in clinical development, multiple product candidates in preclinical development and an active Systems Biology-driven discovery effort. 
MM-398
(Nanotherapeutic)
  • Indication:
  • Description:
  • Target
  • Pancreatic Cancer (2nd line, 2 indications), Colorectal Cancer, Glioma
  • Nanotherapeutic
  • Encapsulated irinotecan
MM-398 is a nanotherapeutic consisting of the chemotherapuetic irinotecan, encapsulated in a liposomal sphere. MM-398 is designed to rely on the natural blood flow of the tumor to direct the therapy directly to the site of the cancer and minimize exposure to non-target cells.
MM-398 in the Clinic
MM-398 is being evaluated in clinical trials for its ability to treat tumors resistant to chemotherapy across multiple types of cancers, including pancreatic, lung, colorectal and glioma. The FDA and the European Medicines Agency granted MM-398 orphan drug designation in 2011 for the treatment of patients with metastatic pancreatic cancer who have previously failed treatment with the chemotherapy drug gemcitabine. Our Phase 3 study, NAPOLI-1 (NAnoliPOsomaL Irinotecan), is currently underway.
posters
http://merrimackpharma.com/library/research/mm-398-preclinical-posters


Phase III prostate cancer trial for 'homing' injection shows improvements


Prostate cancer

Phase III prostate cancer trial for 'homing' injection shows improvements
A new treatment for advanced prostate cancer that homes-in on tumours to deliver a high-energy burst of radiation to cancer cells has shown significant benefits in a large scale clinical trial.
The trial of 921 patients showed that treatment with the radioactive Radium-223 gave men with late-stage prostate cancer an average extra of 15 weeks of life.http://www.pharmaceutical-technology.com/news/newsphase-iii-prostate-cancer-trial-for-homing-injection-shows-benefit?WT.mc_id=DN_News

Monday 22 July 2013

Cancer drug tested in pet dogs is now bound for human trials

File:PAC-1.svg
PAC 1
Thanks to a new $2 million investment, a drug that spurs cancer cells to self-destruct while sparing healthy cells is on the road to human clinical trials. The compound, known as PAC-1, has so far proven safe and has promising anti-cancer effects in cell culture, in mouse models of cancer and in pet dogs with spontaneously occurring lymphomas and osteosarcomas.

If PAC-1 (pack one) makes it through the U.S. Food and Drug Administration’s Investigational New Drug review, the first human (Phase I) clinical trial of the drug will begin in mid-2014. The investor, who wishes to remain anonymous, has an option to invest another $2 million to take the drug into human trials. The clinical work will be conducted at the University of Illinois Cancer Center in Chicago.

http://news.illinois.edu/news/13/0717cancer_drug_PaulHergenrother_TimFan.html






Photo by
L. Brian Stauffer

University of Illinois chemistry professor Paul Hergenrother, left, and veterinary clinical medicine professor Tim Fan led a study of an anti-cancer compound in pet dogs that is now headed for human clinical trials.
PAC-1 (first procaspase activating compound) is a synthesized chemical compound that selectively induces apoptosis, or cell suicide, in cancerous cells. PAC-1 has shown good results in mouse models and is being further evaluated for use in humans. In 2010 a published study showed PAC-1 to be safe to research dogs, and a second study published later that same year reported that a PAC-1 derivative (called S-PAC-1) was well tolerated in a small Phase I Clinical Trial of pet dogs with lymphoma. Even at low doses of S-PAC-1, tumors regressed in 1/6 dogs, and the disease was stabilized (no additional tumor growth) in 3/6 dogs

Wednesday 17 July 2013

Sanofi starts dengue vaccine production for 2015 launch

Sanofi starts dengue vaccine production for 2015 launch

Sanofi starts dengue vaccine production for 2015 launch

Sanofi Pasteur is poised to produce the first validation batches of their dengue vaccine at the company’s state-of-the-art production centre near Lyon, France.
According to Antoine Quin, manager at the site in Neuville-sur-Saone, the plant has a design capacity of 100 million doses of the vaccine, tetravalent CYD-TDV, annually. Starting around 2015, Sanofi Pasteur expects to manufacture one billion doses over the following decade.
Investing 300 million euros in building and staffing the plant was a substantial gamble for Sanofi, said Guillaume Leroy, dengue vaccine head. The Lyon facility got the green light in 2009, when only Phase II data was available. Although promising, this was far from definitive........................
read all at


more on dengue
Learn about prevention of dengue fever, a disease transmitted by mosquitoes.

Dengue Fever Prevention

Neither vaccine nor drugs for preventing infection are available. The bite of one infected mosquito can result in infection. The risk of being bitten is highest during the early morning, several hours after daybreak, and in the late afternoon before sunset. However, mosquitoes may feed at any time during the day. Aedes mosquitoes typically live indoors and are often found in dark, cool places such as in closets, under beds, behind curtains, and in bathrooms. Travelers should be advised to use insecticides to get rid of mosquitoes in these areas and to select accommodations with well-screened windows or air conditioning when possible. Additionally, travelers should take measures to avoid being bitten by mosquitoes. Long-term travelers and expatriates can take extra precautions to reduce mosquito-breeding sites around their accommodations by emptying and cleaning or covering any standing water (such as in water storage tanks and flowerpot trays).
SOURCE: CDC

Dengue fever facts

  • Dengue fever is a disease caused by a family of viruses that are transmitted by mosquitoes.
  • Symptoms such as headache, fever, exhaustion, severe joint and muscle pain, swollen glands (lymphadenopathy), and rash. The presence (the "dengue triad") of fever, rash, and headache (and other pains) is particularly characteristic of dengue fever.
  • Dengue is prevalent throughout the tropics and subtropics. Outbreaks have occurred recently in the Caribbean, including Puerto Rico, the U.S. Virgin Islands, Cuba, and in Paraguay in South America, and Costa Rica in Central America.
  • Because dengue fever is caused by a virus, there is no specific medicine or antibiotic to treat it. For typical dengue fever, the treatment is purely concerned with relief of the symptoms (symptomatic).
  • The acute phase of the illness with fever and myalgias lasts about one to two weeks.
  • Dengue hemorrhagic fever (DHF) is a specific syndrome that tends to affect children under 10 years of age. It causes abdominal pain, hemorrhage (bleeding), and circulatory collapse (shock).
  • The prevention of dengue fever requires control or eradication of the mosquitoes carrying the virus that causes dengue.
  • There is currently no vaccine available for dengue fever.

What is dengue fever?


Dengue (pronounced DENG-gay) can affect anyone but tends to be more severe in people with compromised immune systems. Because it is caused by one of four serotypes of virus, it is possible to get dengue fever multiple times. However, an attack of dengue produces immunity for a lifetime to that particular serotype to which the patient was exposed.Dengue fever is a disease caused by a family of viruses that are transmitted by mosquitoes. It is an acute illness of sudden onset that usually follows a benign course with symptoms such as headache,fever, exhaustion, severe muscle and joint painswollen glands(lymphadenopathy), and rash. The presence (the "dengue triad") of fever,rash, and headache (and other pains) is particularly characteristic of dengue. Other signs of dengue fever include bleeding gums, severe pain behind the eyes, and red palms and soles.
Dengue goes by other names, including "breakbone" or "dandy fever." Victims of dengue often have contortions due to the intense joint andmuscle pain, hence the name breakbone fever. Slaves in the West Indies who contracted dengue were said to have dandy fever because of their postures and gait.
Dengue hemorrhagic fever is a more severe form of the viral illness. Symptoms include headache, fever, rash, and evidence of hemorrhage in the body. Petechiae (small red or purple splotches or blisters under the skin), bleeding in the nose or gumsblack stools, or easy bruising are all possible signs of hemorrhage. This form of dengue fever can be life-threatening and can progress to the most severe form of the illness, dengue shock syndrome.

Tuesday 16 July 2013

Traditional Chinese medicine - chemistry and application

Traditional Chinese medicine - chemistry and application
Traditional Chinese medicine - chemistry and application

Amongst the many aspects of modern Chinese chemistry described in the Journal of Chemical Research during 2012, are phytochemical investigations into the constituents of traditional Chinese medicines derived from plants and fungi. Such studies have afforded new medicines to treat diseases such as Alzheimer’s, malaria and cancer.

Friday 12 July 2013

Ohr Pharmaceutical Achieves 50% Enrollment Milestone in Squalamine Eye Drop Phase II Clinical Trial

File:Squalamine.png

squalamine

July 10, 2013 /
Ohr Pharmaceutical, Inc. , a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, today announced that it has enrolled the first 60 patients in the Company's ongoing OHR-002 Phase II clinical trial evaluating Squalamine Eye Drops for the treatment of the wet form of age-related macular degeneration ("wet-AMD").
The study is a randomized, double blind, placebo controlled study enrolling patients at more than twenty clinical sites in the U.S. "We are excited to have reached the halfway point in the enrollment of our Squalamine Eye Drop study," said Dr. Irach B. Taraporewala, CEO of Ohr.
"This milestone sets the stage for the planned interim analysis once the 60 patients complete the nine month treatment protocol, and we expect the data to be available in the second quarter of 2014.
" "I am pleased with the continued progress in the trial to evaluate Squalamine Eye Drops for exudative AMD," commented Dr. Jason Slakter, retinal disease specialist at Vitreous-Retina-Macula Consultants of NY, and member of Ohr's scientific advisory board. "The Company's eye drop for treating wet-AMD would potentially offer patients a convenient, self-administered, treatment alternative or adjunct to currently used intravitreal injections directly into the eye. This could be a significant advancement in the future treatment of wet-AMD." Study OHR-002 is a randomized, double blind, placebo controlled Phase II study to evaluate the efficacy and safety of Squalamine Eye Drops for the treatment of wet-AMD.
The study will enroll 120 treatment naive wet-AMD patients at more than twenty clinical sites in the U.S., who will be treated with Squalamine Eye Drops or placebo eye drops twice daily for a nine month period.
The primary and secondary endpoints include visual acuity parameters, need for rescue intravitreal injections, and safety. The protocol includes an interim analysis upon the completion of the treatment period in 50% of the patients (60). More information on the clinical trial can be found at clinicaltrials.gov. About Ohr Pharmaceutical, Inc. Ohr Pharmaceutical, Inc. (NasdaqCM:OHRP) is a pharmaceutical company dedicated to the clinical development of new drugs for underserved therapeutic needs in large and growing markets. The Company is focused on advancing its pipeline products currently in phase II clinical development: Squalamine Eye Drops for the treatment of the wet form of age-related macular degeneration, and OHR/AVR118 for the treatment of cancer cachexia. Additional information on the Company can be found at www.ohrpharmaceutical.com.

Thursday 4 July 2013

Garlic in India

 

 

Garlic in India

Uses of Garlic in India
The ancient Indians had varying views on garlic; but, for the most part, it was considered to be highly beneficial to the body. Ancient Sanskrit writings, dating as far back as 5,000 years ago, described the healing properties of garlic. In fact, the ancient medical practice of Ayurveda, which is still practised today, promoted garlic as one of the most important herbs. It recommends garlic in over 100 formulations for treating stomach, liver, tumor, asthma and other similar problems.

The Charaka Samhita is the oldest surviving Ayurvedic text, dating back to 200 BCE to 200 CE (AD), and suggests using garlic for alleviating:

  • worms
  • piles
  • leukoderma
  • leprosy
  • epilepsy
  • heart disease
  • fainting
  • arthritis
  • rheumatism
  • chronic rhinitis
  • baldness.
 It was also included in the diet of nursing mothers to encourage milk secretion in nursing mothers and was hung to protect against evil spirits.

Other Ayurvedic teachings recommend garlic for:

  • arteriosclerosis
  • pain
  • cholera
  • dysentery
  • indigestion
  • constipation
  • appetite loss
  • fatigue
  • typhoid
  • tuberculosis
  • cough
  • fractures
It is also advocated for improving eyesight, intelligence, sexual debility, and impotency.

On the other hand, the ancient Indians believed garlic was a natural aphrodisiac that inspired lust and stimulated passions and, as a result, holy men, monks, widows, adolescents, and fasting persons were forbidden from consuming garlic. In addition, it was considered to be rajasic food; which meant it had unsettling effects on the body and devotees on the path to spiritual enlightenment were advised against eating it. The Buddists, Jains, Greeks and Romans also shared these sentiments; however, some believe the mild irritation garlic caused in the genitourinary tract may have resulted in its aphrodisiac and rajasic status.
References:
  1. Charaka Samhita (Handbook on Ayurveda), edited by G. Van Loon (2002)

Chocolate as medicine: a quest over the centuries



The rehabilitation of chocolate has occurred only in recent times. The pages of scientific magazines have been positively recaptured and chocolate’s reputation is being restored to the value that Carl Linnaeus credited to this food, when he named the generous plant Theobroma cacao, the food of the gods
read all at
http://www.rsc.org/chemistryworld/2013/07/chocolate-medicine-wilson-hurst

Monday 1 July 2013

Verona Pharma Plc Peer-Reviewed Paper Suggests RPL554 With Glycopyrrolate, Or Other Muscarinic Receptor Antagonists, Produces Synergistic Bronchodilation





RPL554

Verona Pharma Plc ("Verona Pharma" Or The "Company") Peer-Reviewed ...

Wall Street Journal
Verona Pharma is developing first-in-class drugs to treat respiratory disease, such as COPD, asthma and chronic, severe cough. The Company has three drug programmes, two of which are in Phase II. The lead programme, RPL554, is an innovative dual ...

read all at
http://online.wsj.com/article/PR-CO-20130701-900428.html?mod=googlenews_wsj



RPL-554 (LS-193,855) is a drug which acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and antiinflammatory effects.[1] It is being developed by Verona Pharma as a potential treatment for asthma and hay fever, and is currently in clinical trials.[2][3]
  1.  Boswell-Smith V, Spina D, Oxford AW, Comer MB, Seeds EA, Page CP. The Pharmacology of Two Novel Long-Acting Phosphodiesterase 3/4 Inhibitors, RPL554 (9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl) -3,4,6,7-tetrahydro-2H-pyrimido(6,1-a)isoquinolin-4-one) and RPL565 (6,7-Dihydro-2-(2,6-diisopropylphenoxy)-9,10-dimethoxy-4H-pyrimido(6,1-a)isoquinolin-4-one). Journal of Pharmacology and Experimental Therapeutics 2006; 318(2):840-848.
  2.  Verona Pharma Plc - Lead Drug RPL554
  3.  Asthma and hay fever drug tested. BBC News, Wednesday 10 September 2008


Friday 28 June 2013

WORLD DRUG TRACKER | join LinkedIn Group

WORLD DRUG TRACKER | LinkedIn


in.linkedin.com/groups/WORLD-DRUG-TRACKER-5055643

Jun 7, 2013 – To track information on drugs on worldwide basis, all aspects covered, A group by DR ANTHONY MELVIN CRASTO Ph.D.

Alexion’s Soliris® (eculizumab) Receives Orphan Drug Designation for the Treatment of Neuromyelitis Optica (NMO)



Structure of eculizumab. Eculizumab was engineered to reduce immunogenicity and eliminate effector function. Human IgG2 and IgG4 heavy-chain sequences were combined to form a hybrid constant region that is unable to bind Fc receptors or to activate the complement cascade. Eculizumab exhibits high affinity for human C5, effectively blocking its cleavage and downstream proinflammatory and cell lytic properties. Reprinted from Rother et al with permission.  

Alexion's Soliris® (eculizumab) Receives Orphan Drug Designation for the ...

Fort Mills Times
In a Phase 2 study presented at the 2012 annual meeting of the American Neurological Association (ANA), Soliris treatment was associated with a significant reduction in the frequency of relapses (recurring attacks) in patients with severe, relapsing ...

http://www.fortmilltimes.com/2013/06/27/2789656/alexions-soliris-eculizumab-receives.html


Eculizumab (INN and USAN; trade name Soliris) is a humanized monoclonal antibody that is a first-in-class terminal complement inhibitor and the first therapy approved for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare, progressive, and sometimes life-threatening disease characterized by excessive destruction of red blood cells (hemolysis). It costs £400,000 (US$600,000) per year per patient

Eculizumab also is the first agent approved for the treatment of atypical hemolytic uremic syndrome (aHUS), an ultra-rare genetic disease that causes abnormal blood clots to form in small blood vessels throughout the body, leading to kidney failure, damage to other vital organs and premature death.

In clinical trials in patients with PNH, eculizumab was associated with reductions in chronic hemolysis, thromboembolic events, and transfusion requirements, as well as improvements in PNH symptoms, quality of life, and survival.Clinical trials in patients with aHUS demonstrated inhibition of thrombotic microangiopathy (TMA),the formation of blood clots in small blood vessels throughout the body, including normalization of platelets and lactate dehydrogenase (LDH), as well as maintenance or improvement in renal function.

Eculizumab was discovered and developed by Alexion Pharmaceuticals and is manufactured by Alexion. It was approved by the United States Food and Drug Administration (FDA) on March 16, 2007 for the treatment of PNH, and on September 23, 2011 for the treatment of aHUS. It was approved by the European Medicines Agency for the treatment of PNH on June 20, 2007, and on November 24, 2011 for the treatment of aHUS. Eculizumab is currently being investigated as a potential treatment for other severe, ultra-rare disorders.






Celgene buys MophoSys for myeloma antibody development


Celgene buys MophoSys for myeloma antibody development
German biopharmaceutical company MorphoSys will jointly develop an antibody for the treatment of multiple myeloma (MM) and leukaemia with Celgene Corporation. 


http://www.pharmaceutical-technology.com/news/newscelegene-buys-mophosys-for-myeloma-antibody-development?WT.mc_id=DN_News