Monday 5 August 2013

Garcinia Cambogia for Weight Loss

If you are an avid user of weight loss products or are interested in starting a diet then you may be curious about Garcinia Cambogia and how effective it is for weight loss. There is nothing worse than searching for information on weight loss products. Your search engine transforms from a helpful, information tool into a long ad that only links you to websites that are trying to sell you a product rather than actually give you any useful information. This is true whether or not the product is any good. Here are some facts on the weight loss product Garcinia Cambogia: it suppresses an enzyme known as citrate lyase and it increases serotonin levels in the brain.


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Sunday 4 August 2013

Cinnamon's Infection and Diabetes-Fighting Properties Revealed

Cinnamon's Infection and Diabetes-Fighting Properties Revealed
Cinnamon's medicinal potential is as rich and complex as its flavor and aroma, with blood sugar balancing and infection fighting top on the list.
Cinnamon is a familiar spice, but few are aware of just how diverse are its medicinal properties.  TheUS National Library of Medicine houses well over 1300 abstracts on the subject of the various forms of cinnamon's potential health benefits.

Medicinal Herbs Show Ability to Replace Diabetes Medication without Side Effects

Medicinal Herbs Show Ability to Replace Diabetes Medication without Side Effects
Researchers from University of Mississippi's School of Pharmacy have conducted an extensive analysis of medicinal plants and proved once again that herbs can replace medications - now diabetes medications. They found that a number of herbs safely modulate cellular PPAR receptors – which means they help regulate glucose, insulin and fat metabolism.
The researchers screened extracts from a total of 263 species of herbs from 94 plant families. They found that eight of the extracts activated the PPARα (Peroxisome proliferator-activated receptor – alpha) and 22 of the plant extracts activated the PPARγ (Peroxisome proliferator-activated receptor – gamma).
Of these, five plant extracts activated both receptors. They were Daphine (Daphne gnidium), Star Anise (Illicium anisatum), Red Cedar (Juniperus virginiana), Haritaki (Terminalia chebula), and Thymelaea (Thymelaea hirsuta).
http://www.greenmedinfo.com/blog/medicinal-herbs-show-ability-replace-diabetes-medication-without-side-effects

Saturday 3 August 2013

MICROENCAPSULATION: ADVANCEMENTS IN TECHNOLOGY AND ITS PATENTS



Microcapsule is a tiny sphere including core material/internal phase or fill, coated with/surrounded by wall know as shell, coating or membrane. The usual size range of the microcapsule lies between 1 to 1000 μm. The technique is usually applied for targeted drug delivery, protection of the molecule and stability if the core material. Microencapsulation system offers potential advantages over conventional drug delivery systems and also established as unique carrier systems for many pharmaceuticals. This article contains the traditional and the recent techniques, including their patents, for the preparation of microcapsules. Solvent exchange method, coacervation, polymerization, hot melts etc are several recent techniques are used for the preparation of the microcapsules. The microencapsulation technique, as Novel drug Delivery System (NDDS), is widely applied for delivery of probiotics, drugs, pesticide, food etc. Although significant advances have been made in the field of microencapsulation, still many challenges need to be rectified during the appropriate selection of core materials, coating materials and process techniques.... read all at
http://www.pharmatutor.org/articles/microencapsulation-advancements-technology-patents

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Thursday 1 August 2013

Alexza Pharmaceuticals Announces European Launch of ADASUVE® (Staccato® Loxapine)



LOXAPINE

MOUNTAIN VIEW, Calif., July 30, 2013 /PRNewswire/ -- Alexza Pharmaceuticals, Inc. (ALXA) today announced that the company's commercial partner Grupo Ferrer Internacional, S.A. has initiated sales of ADASUVE® inhalation powder, pre-dispensed (Staccato® Loxapine) in the European Union ("EU").  ADASUVE is now available in Germany.  The first sale and shipment of product by Ferrer triggers a $1.25 million milestone payment to Alexza, pursuant to the Company's collaboration agreement with Ferrer.

http://finance.yahoo.com/news/alexza-pharmaceuticals-announces-european-launch-130000571.html


Loxapine (LoxapacLoxitane) is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. It is a member of the dibenzoxazepine class and structurally related to clozapine (which belongs to the chemically akin class ofdibenzodiazepines). Several researchers have argued that Loxapine may behave as an atypical antipsychotic.
Loxapine may be metabolized by N-demethylation to amoxapine, a tetracyclic antidepressant





Schmutz, J.; Kunzle, F.; Hunziker, F.; Gauch, R.; Helv. Chim. Acta 1967, 50, 245.