BEXICASERIN

 

Bexicaserin

https://newdrugapprovals.org/2025/04/15/bexicaserin/

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REPROXALAP

 

REPROXALAP

https://newdrugapprovals.org/2020/11/13/reproxalap/

Somapacitan

 FPTIPLSRLF DNAMLRAHRL HQLAFDTYQE FEEAYIPKEQ KYSFLQNPQT SLCFSESIPT

PSNREETQQK SNLELLRISL LLIQSWLEPV QFLRSVFANS CVYGASDSNV YDLLKDLEEG
IQTLMGRLED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY GLLYCFRKDM DKVETFLRIV
QCRSVEGSCG F
(Disulfide bridge: 53-165, 182-189)

Somapacitan

READ AT

https://newdrugapprovals.org/2020/09/15/somapacitan-%e3%82%bd%e3%83%9e%e3%83%91%e3%82%b7%e3%82%bf%e3%83%b3/

CLICK LINK

https://mesothelioma.net/mesothelioma/ 

Mesothelioma Cancer

Mesothelioma is a rare form of cancer that’s most often caused by asbestos exposure. It usually forms in the lungs of those who have been exposed to this deadly toxin, but sometimes occurs in the abdominal area or the area around the heart. There are a number of therapies available that can help prolong survival and minimize symptoms and discomfort, but in most cases the cancer is too aggressive and too advanced at the time of diagnosis to be cured. This disease specifically impacts a thin membrane that protects the lungs, heart and organs within the abdominal cavity and enables them to function properly. This is called the mesothelium and the majority of cases of this type of cancer affect the pleura, the mesothelium that lines the lungs.

mesothelioma.net, one of the most comprehensive online resources for mesothelioma asbestos health and safety information.

Strigolactones: a plant phytohormone as novel anti-inflammatory agents

Strigolactones: a plant phytohormone as novel anti-inflammatory agents

Med. Chem. Commun., 2018, Advance Article
DOI: 10.1039/C7MD00461C, Research Article

Jun-Xia Zheng, Yu-Shui Han, Jin-Cai Wang, Hui Yang, Hao Kong, Kang-Jia Liu, Si-Yu Chen, Yi-Rui Chen, Yi-Qun Chang, Wei-Min Chen, Jia-Liang Guo, Ping-Hua Sun
Strigolactones (SLs), a representative SL, GR24 and its reductive products of D-ring were synthesized and their anti-inflammatory activities were fully evaluated on both in vitro and in vivo models

Strigolactones: a plant phytohormone as novel anti-inflammatory agents

http://pubs.rsc.org/en/Content/ArticleLanding/2018/MD/C7MD00461C?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FMD+%28RSC+-+Med.+Chem.+Commun.+latest+articles%29#!divAbstract

Jun-Xia Zheng,a  Yu-Shui Han,c  Jin-Cai Wang,c  Hui Yang,c  Hao Kong,c  Kang-Jia Liu,c  Si-Yu Chen,c  Yi-Rui Chen,b  Yi-Qun Chang,c  Wei-Min Chen,c  Jia-Liang Guo*b  and  Ping-Hua Sun*c 

 Author affiliations

*Corresponding authors

aSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, PR China

bSchool of Stomatology and Medicine, Foshan University, Foshan, PR China
E-mail: janalguo@126.com
Tel: +86 2085224497

cCollege of Pharmacy, Jinan University, Guangzhou, PR China

Abstract

Strigolactones (SLs) are a novel class of plant hormones with enormous potential for the prevention and treatment of inflammation. To further investigate the anti-inflammatory activities of SLs, a representative SL, GR24, and the reductive products of its D-ring were synthesized and their anti-inflammatory activities were fully evaluated on both in vitroand in vivo models. Among these compounds, the two most active optical isomers (2aand 6a) demonstrated strong inhibitory activity on the release of inflammatory cytokines, including nitric oxide (NO), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) by blocking the nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways; they also greatly inhibited the migration of neutrophils and macrophages in fluorescent protein labeled zebrafish larvae. These results identified the promising anti-inflammatory effects of SLs, and suggested that both the absolute configuration of SL and the α,β-unsaturated D-ring structure are essential for the observed anti-inflammatory activity.

///////////////Strigolactones, phytohormone, anti-inflammatory agents

Register Today for the ACS Symposium in India on Recent Advances in Drug Development, 11-12 November 2016 in Hyderabad, India

Inaugural ACS Industry Symposium, 11-12 November 2016 in Hyderabad, India

Recent Advances in Drug Development

Register Today for the ACS Symposium in India on Recent Advances in Drug Development

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Register now for the inaugural ACS Industry Symposium, 11-12 November 2016 in Hyderabad, India. Be sure to secure your seat today as rates will increase on 27 October!

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The theme of the Symposium is Recent Advances in Drug Development. The event will feature lectures by the world's leading researchers and experts in the pharma industry, including:

• Dr. Peter Senter of Seattle Genetics
• Dr. Jagath Reddy Junutula of Cellerant Therapeutics, Inc.
• Dr. Ming-Wei Wang of the Shanghai Institute of Materia Medica, Chinese Academy of Sciences

This is an exclusive event being organized in partnership with Dr. Reddy's Laboratories for pharma professionals throughout India. Space is limited so register today!

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Register today to ensure your access to the ACS Industry Symposium. We look forward to seeing you in Hyderabad in November.

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/////// ACS Symposium, Recent Advances in Drug Development, 11-12 November 2016, Hyderabad, India, dr reddys, cas