Awakening to New Drugs against Sleeping Sickness

Awakening to New Drugs against Sleeping Sickness

Structure–activity relationships and optimization of triazine nitriles as rhodesain inhibitors
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New Route to Anticancer Agent Quinocarcin

 

Synthesis of quinocarcin through a convergent strategy based on Sonogashira coupling and gold(I)-catalyzed hydroamination
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Hope for Hepatitis Drug

Hope for Hepatitis Drug

A straightforward synthesis of an antiviral drug, entecavir, to treat hepatitis B has industrial scale-up potential
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Scientists Uncover How Grapefruits Provide a Secret Weapon in Medical Drug Delivery

Grapefruit, hybrid citrus.

Scientists Uncover How Grapefruits Provide a Secret Weapon in Medical Drug Delivery
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Reducing caloric intake delays nerve cell loss

Reducing caloric intake delays nerve cell loss

Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May 22 issue of The Journal of Neuroscience. The findings could one day guide researchers to discover drug alternatives that slow … more…

Scientists sequence genome of ‘sacred lotus,’ may hold anti-aging secrets

Scientists sequence genome of ‘sacred lotus,’ may hold anti-aging secrets

A team of 70 scientists from the U.S., China, Australia and Japan reports having sequenced and annotated more than 86 percent of the genome of the “sacred lotus,” which is believed to have a powerful genetic system that repairs genetic defects, and may hold secrets about aging successfully. The Nelumbo nucifera plant is revered in … more…

Do salamanders hold the solution to regeneration

Do salamanders hold the solution to regeneration

Salamanders’ immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have found. In research published in the Proceedings of the National Academy of Sciences (open access), researchers from the Australian Regenerative Medicine Institute (ARMI) at … more…