Monday, 20 June 2016

(±)-Integrifolin, Compound from plants keeps human cancer cells from multipying


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CAS 89647-87-0
C15 H18 O4, 262.30
Azuleno[4,​5-​b]​furan-​2(3H)​-​one, decahydro-​4,​8-​dihydroxy-​3,​6,​9-​tris(methylene)​-​, (3aR,​4R,​6aR,​8S,​9aR,​9bR)​-
  • Azuleno[4,5-b]furan-2(3H)-one, decahydro-4,8-dihydroxy-3,6,9-tris(methylene)-, [3aR-(3aα,4β,6aα,8β,9aα,9bβ)]-
  • (3aR,4R,6aR,8S,9aR,9bR)-Decahydro-4,8-dihydroxy-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one
  • 8-epi-Deacylcynaropicrin
  • 8β-Hydroxyzaluzanin C
  • Integrifolin
  • Integrifolin (guaianolide)
Paper
thumbnail image: Total Synthesis of (±)-Integrifolin

(±)-Integrifolin

Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Total Synthesis of (±)-Integrifolin

Compound from plants keeps human cancer cells from multipying
Read more at Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

(±)-Integrifolin
Banksia integrifolia
Coast Banksia
Family: Proteaceae
Banksia integrifolia is a tall shrub or small tree 6 - 16m tall. It is common in sandy coastal areas, but also grows in the forests of tablelands. The light grey bark is hard and rough.
Mature leaves 5 -10 cm long, are stiff, entire (untoothed), dull dark green above and hairy-white underneath. They are generally lanceolate. Younger leaves are irregularly toothed and shorter than the mature leaves. The species name 'integrifolia' means whole-leaved.
The pale yellow flower spikes of Banksia integrifolia range from 7-14cm long and 7cm wide. The bent styles emerge from individual flowers on the spike, straightening and spreading.
A short time after flowering, the seed pods protrude cleanly from the woody cone and open to shed black, papery, winged seeds.
Banksia integrifolia flowers from January to June.
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///////(±)-Integrifolin,  human cancer cells,  multipying
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