Tuesday 11 June 2013

Targeting Pol I to Selectively Activate p53 and Kill Cancer Cells

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Targeting Pol I to Selectively Activate p53 and Kill Cancer Cells

Cancer is a disease of dysregulated cellular growth and signaling characterized by the loss or gain of function-through mutation or epigenetic change-of important regulatory proteins and cellular processes. Foremost among these is the tumor suppressor protein known as p53.


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